---
type: "Bill"
title: "Nonprescription Ephedrine Products"
description: "AN ACT TO AMEND THE SOUTH CAROLINA CODE OF LAWS BY AMENDING SECTION 44-53-398, RELATING TO THE SALE OF PRODUCTS CONTAINING EPHEDRINE, PSEUDOEPHEDRINE, OR PHENYLPROPANOLAMINE, SO AS TO REQUIRE THAT MANUFACTURERS OF THESE PRODUCTS PAY MONTHLY FEES ASSOCIATED WITH DATA COLLECTION, TO ESTABLISH A PENALTY FOR MANUFACTURERS THAT FAIL TO COMPLY, AND FOR OTHER PURPOSES. - RATIFIED TITLE"
jurisdiction: "us/states/sc"
legislature: "South Carolina General Assembly"
session: "2025-2026"
identifier: "H 4382"
citation: "South Carolina H 4382 (2025-2026)"
classification: ["bill"]
subjects: []
status: "enacted"
primary_sponsors: ["Sessions"]
version_count: 8
action_count: 24
vote_count: 3
first_action: "2025-04-23"
last_action: "2026-06-05"
source: "openstates"
source_identifier: "ocd-bill/ef9341a9-096a-4d38-a62d-24b7dd948225"
source_url: "https://www.scstatehouse.gov/billsearch.php?billnumbers=4382&session=126&summary=B"
source_hash: "1396cbb096e73ff18beafc6db845fd49dd5aa773cc1787165119627d643fc0ba"
vintage: "2026-07-01"
source_snapshot: "https://data.openstates.org/daily/2026-07-01/public.pgdump"
retrieved_at: "2026-07-06"
confidence: "reported"
tags: ["legislation", "bill", "us-sc"]
---

# South Carolina H 4382 (2025-2026) — Nonprescription Ephedrine Products

AN ACT TO AMEND THE SOUTH CAROLINA CODE OF LAWS BY AMENDING SECTION 44-53-398, RELATING TO THE SALE OF PRODUCTS CONTAINING EPHEDRINE, PSEUDOEPHEDRINE, OR PHENYLPROPANOLAMINE, SO AS TO REQUIRE THAT MANUFACTURERS OF THESE PRODUCTS PAY MONTHLY FEES ASSOCIATED WITH DATA COLLECTION, TO ESTABLISH A PENALTY FOR MANUFACTURERS THAT FAIL TO COMPLY, AND FOR OTHER PURPOSES. - RATIFIED TITLE

## Version chain

The bill's text revisions, in order — the diff chain from filing to enrollment.

1. **Filed** (filed) — [source](https://www.scstatehouse.gov/sess126_2025-2026/bills/4382.htm)
2. **04/02/2026** (committee substitute) — [source](https://www.scstatehouse.gov/sess126_2025-2026/prever/4382_20260402.htm)
3. **04/23/2025** (committee substitute) — [source](https://www.scstatehouse.gov/sess126_2025-2026/prever/4382_20250423.htm)
4. **04/29/2026** (committee substitute) — [source](https://www.scstatehouse.gov/sess126_2025-2026/prever/4382_20260429.htm)
5. **05/07/2026** (committee substitute) — [source](https://www.scstatehouse.gov/sess126_2025-2026/prever/4382_20260507.htm)
6. **05/12/2026** (committee substitute) — [source](https://www.scstatehouse.gov/sess126_2025-2026/prever/4382_20260512.htm)
7. **05/13/2026** (committee substitute) — [source](https://www.scstatehouse.gov/sess126_2025-2026/prever/4382_20260513.htm)
8. **05/14/2026** (committee substitute) — [source](https://www.scstatehouse.gov/sess126_2025-2026/prever/4382_20260514.htm)

## Votes

- Passage of Bill — **112–0** (pass) · lower
- Concur in Senate Amendments — **111–0** (pass) · lower
- 2nd Reading — **46–0** (pass) · upper

## Sponsors

- Sessions — primary (person)

## Timeline

The legislative action history — every referral, reading, and vote.

- **2025-04-23** Introduced and read first time `introduction, reading-1`
- **2025-04-23** Referred to Committee on Labor, Commerce and Industry `referral-committee`
- **2026-04-02** Committee report: Favorable with amendment Labor, Commerce and Industry `committee-passage-favorable`
- **2026-04-15** Requests for debate-Rep(s). Frank, Edgerton, Pace, Beach, Harris, Gilreath, Cromer, Terribile
- **2026-04-23** Debate adjourned
- **2026-04-29** Amended `amendment-passage`
- **2026-04-29** Read second time `reading-2`
- **2026-04-29** Roll call Yeas-112 Nays-0
- **2026-04-30** Read third time and sent to Senate `passage, reading-3`
- **2026-04-30** Introduced and read first time `introduction, reading-1`
- **2026-04-30** Referred to Committee on Medical Affairs `referral-committee`
- **2026-05-07** Committee report: Favorable Medical Affairs `committee-passage-favorable`
- **2026-05-12** Amended `amendment-passage`
- **2026-05-12** Read second time `reading-2`
- **2026-05-12** Roll call Ayes-46 Nays-0
- **2026-05-13** Scrivener's error corrected
- **2026-05-13** Read third time and returned to House with amendments `passage, reading-3`
- **2026-05-14** Scrivener's error corrected
- **2026-05-14** Concurred in Senate amendment and enrolled
- **2026-05-14** Roll call Yeas-111 Nays-0
- **2026-05-15** Ratified R 248
- **2026-05-19** Signed By Governor `executive-signature`
- **2026-06-05** Effective date 05/19/26
- **2026-06-03** Act No. 235

## Source

OpenStates / OpenCivicData bulk snapshot [2026-07-01](https://data.openstates.org/daily/2026-07-01/public.pgdump); origin `ocd-bill/ef9341a9-096a-4d38-a62d-24b7dd948225`. Confidence: reported (aggregated from official South Carolina legislature records).