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---
type: "Bill"
title: "Patients' Right to Try Individualized Treatments"
description: "The act allows, but does not require, an eligible patient to request from a manufacturer the manufacturer's individualized investigational drug, biological product, or device, which is a drug, biological product, or device that is unique and produced exclusively for use by an individual patient based on the patient's own genetic profile. The manufacturer must be operating within an institution that operates under federal rules for the protection of human subjects."
jurisdiction: "us/states/co"
legislature: "Colorado General Assembly"
session: "2025A"
identifier: "HB 25-1270"
citation: "Colorado HB 25-1270 (2025A)"
classification: ["bill"]
subjects: []
status: "enacted"
primary_sponsors: ["Barbara Kirkmeyer", "Lindsay Gilchrist", "Lindsey Daugherty", "Rose Pugliese"]
version_count: 8
action_count: 13
vote_count: 2
first_action: "2025-02-18T07:00:00+00:00"
last_action: "2025-05-19T06:00:00+00:00"
source: "openstates"
source_identifier: "ocd-bill/c716cdfc-bb18-4758-a944-361beb594e8b"
source_url: "https://leg.colorado.gov/bills/hb25-1270"
source_hash: "c181c22bdab0ec026c483410f53e16c653fbe5dfb97faf2f593b9e0abb6a4dc7"
vintage: "2026-07-01"
source_snapshot: "https://data.openstates.org/daily/2026-07-01/public.pgdump"
retrieved_at: "2026-07-06"
confidence: "reported"
tags: ["legislation", "bill", "us-co"]
---
# Colorado HB 25-1270 (2025A) — Patients' Right to Try Individualized Treatments
The act allows, but does not require, an eligible patient to request from a manufacturer the manufacturer's individualized investigational drug, biological product, or device, which is a drug, biological product, or device that is unique and produced exclusively for use by an individual patient based on the patient's own genetic profile. The manufacturer must be operating within an institution that operates under federal rules for the protection of human subjects.
## Version chain
The bill's text revisions, in order — the diff chain from filing to enrollment.
1. **Committee Amendment** (committee substitute) — [source](https://leg.colorado.gov/sites/default/files/2025a_hb1270_s_hhs_001.pdf)
2. **Engrossed (03/13/2025)** (committee substitute) — [source](https://leg.colorado.gov/sites/default/files/documents/2025A/bills/2025a_1270_eng.pdf)
3. **Final Act (05/01/2025)** (committee substitute) — [source](https://leg.colorado.gov/sites/default/files/documents/2025A/bills/2025a_1270_enr.pdf)
4. **Introduced (02/18/2025)** (committee substitute) — [source](https://leg.colorado.gov/sites/default/files/documents/2025A/bills/2025a_1270_01.pdf)
5. **Reengrossed (03/14/2025)** (committee substitute) — [source](https://leg.colorado.gov/sites/default/files/documents/2025A/bills/2025a_1270_ren.pdf)
6. **Rerevised (04/14/2025)** (committee substitute) — [source](https://leg.colorado.gov/sites/default/files/documents/2025A/bills/2025a_1270_rer.pdf)
7. **Revised (04/11/2025)** (committee substitute) — [source](https://leg.colorado.gov/sites/default/files/documents/2025A/bills/2025a_1270_rev.pdf)
8. **Signed Act (05/19/2025)** (committee substitute) — [source](https://leg.colorado.gov/sites/default/files/2025a_1270_signed.pdf)
## Votes
- BILL — **64–0** (pass) · lower
- BILL — **33–0** (pass) · upper
## Sponsors
- Barbara Kirkmeyer — primary (person)
- Lindsay Gilchrist — primary (person)
- Lindsey Daugherty — primary (person)
- Rose Pugliese — primary (person)
- A. Boesenecker — cosponsor (person)
- B. Bradley — cosponsor (person)
- B. Marshall — cosponsor (person)
- B. Pelton — cosponsor (person)
- B. Titone — cosponsor (person)
- C. Barron — cosponsor (person)
- C. Clifford — cosponsor (person)
- C. Espenoza — cosponsor (person)
- C. Kipp — cosponsor (person)
- C. Simpson — cosponsor (person)
- D. Johnson — cosponsor (person)
- D. Michaelson Jenet — cosponsor (person)
- D. Roberts — cosponsor (person)
- E. Hamrick — cosponsor (person)
- I. Jodeh — cosponsor (person)
- J. Amabile — cosponsor (person)
- J. Bacon — cosponsor (person)
- J. Caldwell — cosponsor (person)
- J. Jackson — cosponsor (person)
- J. McCluskie — cosponsor (person)
- K. McCormick — cosponsor (person)
- K. Stewart — cosponsor (person)
- K. Wallace — cosponsor (person)
- L. Cutter — cosponsor (person)
- L. Feret — cosponsor (person)
- L. Frizell — cosponsor (person)
- L. Garcia Sander — cosponsor (person)
- L. García — cosponsor (person)
- M. Catlin — cosponsor (person)
- M. Duran — cosponsor (person)
- M. Froelich — cosponsor (person)
- M. Lindsay — cosponsor (person)
- M. Martinez — cosponsor (person)
- M. Rutinel — cosponsor (person)
- N. Hinrichsen — cosponsor (person)
- R. English — cosponsor (person)
- R. Gonzalez — cosponsor (person)
- R. Keltie — cosponsor (person)
- R. Taggart — cosponsor (person)
- R. Weinberg — cosponsor (person)
- S. Bird — cosponsor (person)
- S. Bright — cosponsor (person)
- S. Camacho — cosponsor (person)
- S. Lieder — cosponsor (person)
- T. Story — cosponsor (person)
- T. Winter — cosponsor (person)
## Timeline
The legislative action history — every referral, reading, and vote.
- **2025-05-19T06:00:00+00:00** Governor Signed `executive-signature`
- **2025-05-02T06:00:00+00:00** Sent to the Governor `executive-receipt`
- **2025-05-01T06:00:00+00:00** Signed by the President of the Senate
- **2025-05-01T06:00:00+00:00** Signed by the Speaker of the House
- **2025-04-14T06:00:00+00:00** Senate Third Reading Passed - No Amendments `passage, reading-3`
- **2025-04-11T06:00:00+00:00** Senate Second Reading Special Order - Passed - No Amendments
- **2025-04-10T06:00:00+00:00** Senate Committee on Health & Human Services Refer Unamended - Consent Calendar to Senate Committee of the Whole `committee-passage`
- **2025-03-19T06:00:00+00:00** Introduced In Senate - Assigned to Health & Human Services `introduction`
- **2025-03-14T06:00:00+00:00** House Third Reading Passed - No Amendments `passage, reading-3`
- **2025-03-13T06:00:00+00:00** House Second Reading Special Order - Passed - No Amendments
- **2025-03-10T06:00:00+00:00** House Second Reading Laid Over Daily - No Amendments
- **2025-03-05T07:00:00+00:00** House Committee on Health & Human Services Refer Unamended to House Committee of the Whole `committee-passage, referral-committee`
- **2025-02-18T07:00:00+00:00** Introduced In House - Assigned to Health & Human Services `introduction`
## Source
OpenStates / OpenCivicData bulk snapshot [2026-07-01](https://data.openstates.org/daily/2026-07-01/public.pgdump); origin `ocd-bill/c716cdfc-bb18-4758-a944-361beb594e8b`. Confidence: reported (aggregated from official Colorado legislature records).